Facial · Skin and dark spots
Cosmelan for dark spots and melasma in Medellín
A depigmenting protocol with support at every phase
From $ 3.500.000
- 4.9 on Google · 266 reviews
- 20,000+ patients since 2020 · INVIMA-registered products

- Duration
- 30-min in-office application
- Sessions
- 1 protocol with an at-home phase
- Recovery
- Redness and peeling for several days
- Results
- Gradual, over weeks
- Investment
- from $ 3.500.000
On video
Meet your doctor
Dr. Daniela Díez and the clinic team, in their own words. The videos are in Spanish and play from Instagram.
Before you decide
Is it right for you?
We tell you frankly when this treatment is a good option and when we'd rather assess you first.
Ideal if…
- You're concerned about dark spots, melasma, or hyperpigmentation on your face
- You notice your skin tone looks dull or uneven
- You have the discipline to follow the at-home phase
- You commit to applying sunscreen every day
We assess you first if…
- You're pregnant or breastfeeding
- The area has wounds, infection, or irritation
- You expect to erase dark spots permanently without protecting yourself from the sun
Before you decide
The questions we hear most, answered straight.
- Does it hurt?
- No needles are used. In the first few days you may feel burning, itching, and tightness, which we manage with the soothing cream and the instructions we give you.
- How long does recovery take?
- Your skin usually turns red and peels for several days; many people prefer to spend that time at home.

How we do it at Quantum
A medical protocol, not a catalog
Every plan starts with a consultation: we listen to what you want to achieve, review your medical history and decide whether this treatment is right for you.
- 01
Medical consultation
Before any treatment is applied, we review your case and explain what is possible and what isn't.
- 02
D10 Facial Scanner
Everything starts with a consultation, not a catalog: we analyze your skin and scalp before recommending any treatment.
- 03
Follow-up visit
We review the result with you and adjust the plan if needed.
What it is and how it works
Dark spot treatment (Cosmelan)
Cosmelan is a protocol that regulates the production of melanin, the pigment that forms dark spots, to help even out your skin tone. It starts at the clinic, where we apply the Cosme 1 mask, and continues at home with Cosme 2. The complete protocol also includes sunscreen and a soothing cream.
It's recommended for dark spots, melasma, hyperpigmentation, or a dull facial tone, as long as you can follow the at-home phase consistently and use sunscreen every day: without that, the pigment comes back. We don't perform it during pregnancy or breastfeeding, or on skin that is irritated, broken, or infected.
The in-office application takes about 30 minutes. Over the following days your skin turns red and peels, and improvement appears gradually over weeks; every skin responds differently. The complete protocol starts at $3.500.000 and includes the consultation, the products, and our professional follow-up.
- 01More even tone
- 02In-clinic and at-home phases
- 03Sunscreen and soothing cream included
- 04Professional support
Your session
Step by step
Here's how your treatment goes, from the consultation to the follow-up visit.
- 01
Diagnosis with the facial analyzer
With the facial analyzer, we identify what type of pigment you have and how deep it is, and confirm whether this protocol is right for you.
Medical consultation before starting
- 02
In-clinic phase
In the office, we apply the Cosme 1 mask and tell you how long to leave it on and how to remove it at home.
Done in the office
- 03
At-home phase with follow-up visits
At home, you continue with Cosme 2, plus the soothing cream and sunscreen; at each follow-up visit we review how your skin is progressing.
Regular follow-up visits
Safety and natural results
Less is more
We want you to look like yourself, at your best. These are the criteria we follow in every session.
Original products registered with INVIMA
- 01
Diagnosis comes first
Every dark spot is different, so we confirm the type of pigment before recommending the protocol.
- 02
Written instructions
You leave the clinic with written instructions: how to use each product and when to remove the mask.
- 03
Realistic expectations
Melasma is a chronic condition that can come back; we teach you how to maintain your results.
- 04
Irritation monitoring
Redness and peeling are normal; we check that your skin is reacting the way we expect.
Where we'll see you
In El Poblado's medical tower
Office 516, 5th floor, in the Clínica Medellín building, El Poblado location.
Get directions
Cl. 7 # 39-290Office 516, Floor 5 · El Poblado, Medellín- Monday to Friday
- 9:00 a.m. to 7:00 p.m.
- Saturdays
- 9:00 a.m. to 1:00 p.m.
What backs our care
- 01
Hospital setting
The building where our office is located also houses Clínica Medellín's El Poblado location, with 24-hour emergency care on site.
- 02
Medical director
Dr. Daniela Díez, a physician licensed to practice in Colombia and Argentina, trained in aesthetic medicine (UBA).
- 03
Original products
We work with original INVIMA-registered products.
- 04
Legally registered company
Quantum Estética S.A.S., NIT 901.573.402-4. Medical consultation and medical record for every treatment.
Clínica Quantum is an independent medical practice. We are not part of Clínica Medellín or Grupo Quirónsalud, and our services are not endorsed by them.
Investment
Prices from
Reference prices. Your plan and final price are confirmed at your medical consultation.
| Option | From |
|---|---|
| Complete protocolCosme 1, Cosme 2, sunscreen, soothing cream | $ 3.500.000 |
Includes
- Medical consultation beforehand
- Cosme 1 (in-office application)
- Cosme 2 for the at-home phase
- Sunscreen and soothing cream
- Instructions and professional follow-up
What our patients say
Google reviews
Reviews translated from Spanish.
“The experience was INCREDIBLE, I loved the care. The price was really good for everything they did. They use great technology, they're innovative, and they have the best quality. They're so good that I'm bringing my sister and my boyfriend, because honestly, HIGHLY recommended.”
Antonia Aguirre
A year ago · Google
“She's very professional when advising her patients on each procedure according to their aesthetic needs, and combined with her warmth, that makes the doctor very sound in her medical practice.”
Catalina Serra
2 years ago · Google
“The best clinic, absolutely incredible care, a great (highly trained) team, and I'm very happy with my process. HIGHLY RECOMMENDED.”
Camilo López Posada
8 months ago · Google
Get ready
Care before and after
Before
- 01The week before, avoid sun exposure and exfoliants
- 02Tell us about any creams and medications you use
- 03Plan your schedule around the peeling days
After
- 01Remove the mask exactly at the time we tell you
- 02Apply sunscreen every day, even when you're at home
- 03If you feel burning or tightness, use the soothing cream
- 04Let peeling skin fall off on its own, without pulling it
- 05Keep your follow-up appointments
Frequently asked questions
We answer your questions
Have another question? Message us on WhatsApp and our medical team will answer.
How much does Cosmelan cost?
The complete protocol starts at $3.500.000. That price covers the Cosme 1 mask, the Cosme 2 phase, sunscreen, and the soothing cream.
Does it hurt?
No needles are used. In the first few days you may feel burning, itching, and tightness, which we manage with the soothing cream and the instructions we give you.
How long does recovery take?
Your skin usually turns red and peels for several days; many people prefer to spend that time at home.
How soon will I see results?
Dark spots lighten gradually over the following weeks. How much they improve depends on the type of spot and how closely you follow the at-home phase.
Can the dark spots come back?
Yes, they can come back, especially melasma, with sun exposure or hormonal changes. That's why daily sun protection and maintenance are essential.
Who shouldn't have it?
It isn't recommended during pregnancy or breastfeeding, or on irritated or broken skin. We review your case during your consultation.
Can it be combined with other treatments?
Yes. Depending on your skin, it can later be complemented with depigmenting mesotherapy or microneedling; we decide this at your follow-up.
Follow us on social media
Real cases, procedures and day-to-day life at the clinic, posted by the Quantum team.
Pair it with
Treatments that complement it
- 01Mesotherapy dark spot treatmentMesotherapy, device-based treatment, and cleansings to even out your tone.From $ 2.000.000
- 02Microneedling with depigmenting agentsImproves pores, texture, and dark spots in a single package.From $ 1.000.000
- 03Porcelain facialDeep cleansing and a brightening mask for an even tone.From $ 180.000
Take the first step
Book your personalized consultation
We assess your case, listen to what you want to achieve and design the right plan for you.
Follow us on social media
Real cases, procedures and day-to-day life at the clinic, posted by the Quantum team.






